ISSN Online: 2177-1235 | ISSN Print: 1983-5175

Research on Humans and Animals

Research projects involving humans should comply with the Declaration of Helsinki ( and Resolution 466/2012 ( and 510/2016 ( from the National Health Council (Conselho Nacional de Saúde–CNS). All research involving humans should be evaluated by a Research Ethics Committee (Comitê de Ética em Pesquisa–CEP), and only studies approved by the CEP qualify for publication.

Research using animal models should comply with guidelines of the Basel Declaration ( and the Guide for the Care and Use of Laboratory Animals (Institute of Laboratory Animal Resources, National Academy of Sciences, Washington, USA). The Editorial Board may refuse to publish articles that do not strictly comply with the ethical standards of the research, whether on humans or animals. Identify all drugs and chemicals used in the research, including the names of active ingredients, dosages, and forms of administration, and avoid using commercial and company names.

Clinical trial registration

The Rev Bras Cir Plast. supports the policies for registration of clinical trials by the World Health Organization (WHO) and the International Committee of Medical Journal Editors (ICMJE), recognizing the importance of these initiatives for the registration and international dissemination of clinical studies information open access. Therefore, clinical trials are only acceptable if registered adequately before data collection begins at or an equivalent international repository. The identification number must be registered at the end of the summary.

Within this context, the RBCP adopts the definition of a clinical trial recommended by the WHO, which can be summarized as follows: "any research that prospectively designates humans for one or more interventions to assess their effects on health-related outcomes. Interventions include drugs, cells, and other biological products, surgical, radiological procedures, devices, behavioral therapies, changes in care processes, preventive care, etc. ".


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